Crizotinib Manufacturer/Cas:877399-52-5 /99.8% High purity CAS NO.877399-52-5
- FOB Price: USD: 2.00-5.00 /Metric Ton Get Latest Price
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,T/T,
- Available Specifications:
100(1-25)Metric Ton100(100-100)Metric Ton
- Product Details
Keywords
- 877399-52-5
- Crizotinib
- APIS Manufacturer
Quick Details
- ProName: Crizotinib Manufacturer/Cas:877399-52-...
- CasNo: 877399-52-5
- Molecular Formula: C21H22Cl2FN5O
- Appearance: White or off white powder
- Application: It is suitable for chemical industry s...
- DeliveryTime: ccording to the actual situation
- PackAge: 100g/bag 1kg/bag 25kg/barrels
- Port: Shanghai port, shenzhen port, tianjin ...
- ProductionCapacity: 100 Metric Ton/Day
- Purity: 99%
- Storage: 2 ℃, 25 ℃ dry dark cold storage
- Transportation: Air freight; shipping;DHL;FEDEX;TNT…
- LimitNum: 1 Metric Ton
- Related Substances: Refer to the details
- Residue on Ignition: Refer to the details
- Heavy Metal: ≤20ppm
- Valid Period: 24 month
- Dry weight lessness: ≤0.5%
Superiority
Chinese synonyms: cozotinib; crezotinib; crezotinib API; crezotinib, crezotinib; (R) - 3 - (1 - (2,6 - dichloro - 3 - fluorophenyl) ethoxy) - 5 - - 1H - pyrazole - 4 - yl) pyridine - 2 - amine (crezotinib); gram; crezotinib, CRIZOTINIB; crezotinib;
English Name: Crizotinib
CAS: 877399-52-5
Molecular formula: C21H22Cl2FN5O
Molecular weight: 450.343
EINECS: 1308068-626-2
Oral absorption of a single dose of zolatinib reached an average of 4~6 hours. Two doses of 250 mg of clozotinib per day were administered twice. The steady blood concentration was achieved and maintained within 15 days. The average cumulative rate was 4.8. When the dose exceeded the dose range of 200-300 mg twice a day, the increase of Cmin and AUC was slightly higher than that of dose.
The average absolute bioavailability of clozotinib was 43% (range: 32% - 66%) after a single oral dose of 250 mg.
High fat diet can reduce the AUCinf and Cmax of kazatinib by about 14%. Kazzinib can be served with or without food
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