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Home > Products >  AZD3759/Cas:1626387-80-1 /Assay:99.8%

AZD3759/Cas:1626387-80-1 /Assay:99.8% CAS NO.1626387-80-1

  • FOB Price: USD 1 /Metric Ton Get Latest Price
  • Min.Order: 100 Metric Ton
  • Payment Terms: L/C,D/A,D/P,T/T,Western Union,MoneyGram
  • Available Specifications:

    100(1-25)Metric Ton

  • Product Details

Keywords

  • 1626387-80-1
  • AZD3759
  • AZD-3759

Quick Details

  • ProName: AZD3759/Cas:1626387-80-1 /Assay:99.8%
  • CasNo: 1626387-80-1
  • Molecular Formula: C22H23ClFN5O3
  • Appearance: White or off white powder
  • Application: It is suitable for chemical industry s...
  • DeliveryTime: ccording to the actual situation
  • PackAge: 100g/bag 1kg/bag 25kg/barrels
  • Port: Shanghai port, shenzhen port, tianjin ...
  • ProductionCapacity: 100 Metric Ton/Day
  • Purity: 99%
  • Storage: 2 ℃, 25 ℃ dry dark cold storage
  • Transportation: Air freight; shipping;DHL;FEDEX;TNT…
  • LimitNum: 100 Metric Ton
  • Related Substances: Refer to the details
  • Residue on Ignition: Refer to the details
  • Heavy Metal: ≤20ppm
  • Valid Period: 24 month
  • Dry weight lessness: ≤0.5%

Superiority

Chinese Name: AZD3759

English Name: AZD3759

English alias: 4 - ((3-chloro-2-fluorophenyl) amino) - 7-methoxyquinazolin-6-yl (2R) - 2,4-dimethylpiperazine-1-carboxylate; (R) - 4 - ((3-chloro-2-fluorophenyl) amino) - 7-methoxynazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate;

CAS: 1626387-80-1

Molecular formula: C22H23ClFN5O3

Molecular weight: 459.90100

Exact mass: 459.14700 PSA:79.82000 LogP:4.25800

Appearance and character: white or gray solid.

Melting point: 192.4 degrees C (alcohol, ester), 193.3 degree C (water)

Water solubility: soluble in DMSO

Content: more than 99% pharmaceutical grade

AZD3759 has a very high passive permeability (29.5x10-6 cmc), not a substrate of transmembrane glycoprotein (Pgp), but Kpuu, brain and Kpuu, CSF > 0.5 in immune mice and monkeys.

Preliminary clinical results: Four patients with brain-to-brain NSCLC, three patients with 50 mg*2 per day and one patient with 100 mg*2 per day. Among them, two patients were assessable and one patient was stable. The drug concentration in CSF was 7.7nM and 6nM, approximately equal to the pEGFR IC50 of AZD3759. No side effects were found in the clinic.

Details

1.high quality and competetive price
1)for Pharmaceutical raw materials exported we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price. 
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.
 
2.fast and safe delivery:
1)products can be sent out one or four weeks after payment. tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment. various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate ¡ý99%.
4)for hot sale products we have stock in there for transferring. 
 
3 we have clients throughout the world:
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility. 
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers. 
 

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